Facebook Twitter By Network Indiana – March 10, 2021 0 236 Pinterest Previous articleSouth Bend Cubs hiring for the upcoming seasonNext articleNational Weather Service making enhancements to Severe Thunderstorm Warnings Network Indiana Google+ IndianaLocalNews Facebook Indiana lawmakers to vote on whether to allow delivery robots Pinterest Google+ WhatsApp (“Indiana State Capitol Building” by Drew Tarvin, CC BY 2.0) You’re a step closer to getting your next pizza delivery by robot:The Senate could vote next week to let delivery robots operate alongside pedestrians on streets and sidewalks. It’s not illegal now — Purdue has had robot deliveries for a couple of years. But the bill would explicitly make them legal.Delivery companies including Amazon and FedEx, and businesses including Pizza Hut, Walgreens, and AutoZone, use robot fleets to make immediate short-haul deliveries. The bots are about the size of a picnic cooler and move about as fast as you can walk, with sensors telling them when they need to back up or go around an obstacle.Purdue procurement manager Brett Decker says the giant mountains of plowed snow after last month’s storm stumped the robots, but they’ve otherwise operated problem-free. He says the bots have been overwhelmingly popular, with students able to have food or coffee waiting for them when they leave class or when they arrive for their next one.Jenna Knepper with the local government group AIM says cities and towns are “excited” about the robots, as long as they can set rules on things like where the robots are allowed to operate. The bill authored by Evansville Representative Holli Sullivan (R) would prohibit cities and towns from banning the robots entirely, limiting what they can carry, or regulating their design, but would allow other local rules.FedEx lobbyist Chris Mitchum says the bill is written broadly to allow new robot technologies, as long as they meet basic operating and safety standards.The House unanimously approved the bill last month. Twitter WhatsApp
Morrisons today claimed it had made a “solid start” to its new financial year – despite posting a like-for-like sales decline of 1.8%.It said total sales had risen slightly by 0.8%, excluding fuel.During the quarter six further stores were opened including two Morrisons M locals and 80 convenience stores were added to the pipeline. They are on track to meet their target of having 100 convenience stores open by the end of the year, with 20 opening in the first half.The Fresh Format concept continues to be tailored to new and existing stores and will have been implemented in over 40% of the estate by the end of the current financial year.Dalton Philips, chief executive, said: “Our promotions have been more innovative and we are explaining Morrisons points of difference more effectively.“These efforts were further reinforced by the horsemeat scandal which helped drive increasing customer recognition of Morrisons unique supply chain and approach to meat sourcing. They now understand the Morrisons is best placed to sell food that is what it says it is.”
It’s fair to say that people around the world have been ecstatic about the upcoming Royal Wedding on May 19th. However, we find ourselves asking, “Has the hype gone too far?” after finding out that the nuptials between Prince Harry and Meghan Markle will be released globally on streaming services. Furthermore, for all you vinyl lovers out there, Decca Records has announced that it will be releasing its recording of the ceremony on vinyl after the fact. However, there will also be musical performances during the ceremony, including those by British cellist Sheku Kanneh Mason, Welsh soprano Elin Manahan Thomas, the Choir of St George’s Chapel, and the Kingdom Choir.As the upcoming album’s producer, Anna Barry, noted in a press release, “Capturing the words and music of this Royal Wedding is a great responsibility, knowing how much a permanent record of the event will mean to so many people around the world. Our Decca team will deliver a state of the art recording which captures every nuance of this very happy day and it will be a joy to be a part of the celebrations.”[H/T Pitchfork]
We’ll start this birthday tribute with two undeniable facts: Led Zeppelin was one of the greatest rock bands of all time. A band is really only as good as its drummer. With that in mind, it’s no surprise that Led Zeppelin’s kit man John Bonham is consistently viewed as one of the greatest that ever lived. While Bonham’s life was sadly cut short at the age of 32, his musical legacy lives on through both his son, Jason Bonham, and an impressive catalog from his tenure with Zeppelin.Bonzo was a madman behind the drums, but still managed to keep things grooving like no other. Whether it was following along Jimmy Page’s behemoth solos or Robert Plant’s blues riffing on vocals, Bonham never missed a beat. His hard-hitting style has certainly earned him a place in many fan’s hearts, as the drummer would improvise for many an extended drum solo performance. Whenever that infamous opening riff of the Led Zeppelin II track “Moby Dick” was played live, fans knew to expect some pure drumming from Bonzo.On what would have been his birthday, we salute Bonham with the version of Zeppelin’s “Moby Dick” from a 1970 show in London’s Royal Albert Hall. Feast your ears on this masterpiece of percussion.[Video: Kaushal Bajracharya]Happy birthday John Bonham![Originally published in 2016]
The Wyss Institute’s human-gut-on-a-chip precisely mimics the biochemical and mechanical microenvironment of the human intestine, even rhythmically expanding and contracting cultured human intestinal epithelial cells just as they would inside the gut through the process of peristalsis, as seen here. Credit: Wyss Institute at Harvard University “Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells, and the immune system, but so far it has been impossible to determine how each of these factors contributes to the development of intestinal bowel disease,” said Hyun Jung Kim, former Wyss Technology Development Fellow and first author of the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.The human-gut-on-a-chip technology, however, provides an ideal microenvironment for mimicking the natural conditions of the human intestines in a small-scale, controllable, in vitro platform. The human-gut-on-a-chip was first invented at the Wyss Institute in 2012. Made of a clear, flexible polymer about the size of a computer memory stick, the hollow-channeled microfluidic device simulates the physical structure, microenvironment, peristalsis-like waves and fluid flow of the human intestine.In this latest advance reported in PNAS, the Wyss team showed that the human-gut-on-a-chip’s unique ability to co-culture intestinal cells with living microbes from the normal gut microbiome for an extended period of time — up to two weeks — could give breakthrough insights into how the microbial communities that flourish inside our GI tracts contribute to human health and disease.“The discovery of the microbiome and its significance represents a huge paradigm shift in our understanding of human health — there are more microbes living on us and in us than our own cells,” said Ingber, the Judah Folkman Professor of Vascular Biology at Harvard Medical School and the Vascular Biology Program at Boston Children’s Hospital, and professor of bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences.“Until now, use of traditional culture methods and even more sophisticated organoid cultures have prevented the microbiome from being studied beyond one or two days,” Ingber said. “With our human-gut-on-a-chip, we can not only culture the normal gut microbiome for extended times, but we can also analyze contributions of pathogens, immune cells, and vascular and lymphatic endothelium, as well as model specific diseases to understand complex pathophysiological responses of the intestinal tract.”“There is much to be learned about IBD, as well as how antibiotics impact the microbiome,” said Collins, the Termeer Professor of Bioengineering in the Department of Biological Engineering and Institute for Medical Engineering & Science at the Massachusetts Institute of Technology. “This technology enables one to study in an isolated and controlled manner the complexity of the microbiome and the role different microbial species play in health and disease. It is therefore a highly valuable platform for discovery and clinical translation efforts.”Already the advance has revealed new discoveries into the inner workings of the human intestinal tract and its immune responses. Four small proteins that stimulate inflammation (called cytokines) were found to work in tandem to trigger inflammatory immune responses that damage and irritate the bowel. This discovery could open a new potential therapeutic pathway to treating IBD by “blocking” these cytokine proteins simultaneously.The Wyss team also studied the roles fluid flow and the wave-like peristaltic movement of the gut play in maintaining a dynamic equilibrium of the gut microbiome, finding that absence of peristaltic movement can lead to rampant overgrowth of bacteria completely independent of changes in fluid flow. This could help explain why some patients with IBD and other conditions develop bacterial overgrowth, such as those who develop ileus, a syndrome that can occur after intestinal surgery when there is a prolonged delay in the body’s ability to resume normal peristaltic motions.The Wyss team believes the ability of the human-gut-on-a-chip to culture the microbiome with human gut cells also holds promise for the field of precision medicine, in which a patient’s own cells and gut microbiota one day could be cultured inside a gut-on-a-chip for testing different therapies and identifying an individualized treatment strategy.“Previously the microbiome and its role in human health were largely defined through study of their gene expression, but now, by being able to carry out human experimentation in vitro relating to how the microbiome, human intestinal cells, and human immune components interplay, we hope to gain a much deeper understanding of underlying pathophysiological mechanisms that will hopefully lead to development of new and more effective therapies,” said Ingber.For more information, visit the Wyss Institute website. It’s estimated that as many as a million Americans suffer from inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn’s disease, which cause mild to severe symptoms that at best can be managed and at worst lead to life-threatening complications.While abnormal immune responses are largely responsible for these diseases, issues relating to gut microbiome, intestinal epithelial cells, immune components, and the gut’s rhythmic peristalsis motions can also contribute to and exacerbate symptoms. But until now, scientists have been hard pressed to develop new therapies for treating IBDs because they could not replicate the human gut microenvironment in the laboratory.On Monday, the Wyss Institute for Biologically Inspired Engineering at Harvard University announced that its team had created a model of human intestinal inflammation and bacterial overgrowth in a human-gut-on-a-chip. The team, co-led by Wyss Institute Founding Director Donald Ingber and core faculty member James Collins, leveraged the institute’s proprietary human-organs-on-chips technology to microengineer the model.The advance, reported in the Proceedings of the National Academy of Sciences (PNAS), allows scientists to analyze for the first time how normal gut microbes and pathogenic bacteria contribute to immune responses, and to investigate IBD mechanisms in a controlled model that recapitulates human intestinal physiology.A view from the inside
GENEVA (AP) — The U.N. special envoy for Syria has expressed disappointment after five days of meetings in Geneva between delegations from the Syrian government, opposition and civil society groups aimed at revising the constitution of the war-torn country ended without progress. Geir Pedersen hinted that the Syrian government delegation was to blame for the lack of headway because it rejected a proposal he presented. Syria’s nearly 10-year conflict has killed more than half a million people and displaced half the country’s pre-war population of 23 million, including more than 5 million refugees who now live mostly in neighboring countries.
After an anonymous whistleblower reported a concern in August to the House of Representatives and Senate Intelligence Committees about U.S. President Donald Trump soliciting foreign interference to better his chances in the 2020 election, the complaint was eventually passed along to the Justice Department.From there, on Sept. 24, Speaker of the House Nancy Pelosi announced an impeachment inquiry into Trump for his dealings with Ukrainian President Volodymyr Zelensky.The anonymous whistleblower claims Trump threatened to cut off Ukraine’s foreign aid if the government did not cooperate in the investigation of Democratic presidential candidate Joe Biden. The possibility of impeachment has elicited strong responses throughout the political world, not excluding Notre Dame’s campus.Though the charges facing the president are serious, Dominic Ferrante, senior and president of Notre Dame’s College Republicans, said he is not worried for Trump. “It’s going to come to nothing in the end. I don’t think the House will even end up taking an impeachment vote on it,” Ferrante said. ”On the off chance that the House does vote on it, I think the vote will fail.” First year John Ferletic, a College Republicans officer, said he doesn’t see the recent attempts to impeach the President as legitimate or threatening to his presidency.”Even if the President is impeached by the House, I don’t see an outcome at the moment where the Senate would remove him from office,” Ferletic said.Before voting on impeachment articles, the House of Representatives must investigate the claim regarding the president’s alleged misconduct and determine whether an impeachable offense was committed.If the House votes to impeach Trump, he will then be tried in the Senate. While former U.S. Presidents Andrew Johnson and Bill Clinton were both impeached by the House of Representatives, both were acquitted by the Senate and thus remained in office.Though no official vote has been held on the matter, the House Intelligence Committee is currently conducting an official investigation into the whistleblower’s claims. The impeachment process is long and complicated, and requires both the majority of the House and two-thirds of the Senate to support the action.Ferrante said he is unconcerned about the allegation having a negative effect on Trump’s chances in the 2020 election.“It certainly won’t do any harm. It could potentially ignite the President’s supporters,” Ferrante said. ”I think most of President Trump’s supporters see this as more of the same, more constant attacks by the Democrats to delegitimize President Trump in any way they can.” Ferrante criticized Pelosi and the Democrats for initiating the impeachment inquiry. “They are afraid that none of their candidates can beat President Trump in the 2020 election,” he said. ”I think this is just an attempt to weaken the President and make him vulnerable in that year.”Senior Sheila Gregory, president of Notre Dame’s College Democrats, believes the investigation will reveal damning evidence against President Trump.“Any number of actions President Trump has taken could have been impeachable offenses” Gregory said. ”I think we are on the verge of an avalanche of information.”Gregory said she believes the impeachment inquiry could negatively affect the President’s chance of re-election. “I think an investigation like this will only serve to hurt the president,” Gregory said. ”He is incapable of staying on message in situations like these and when what people see on the news every night is that the President of the United States committed crimes, that will not bode well for his chances.” Gregory said the Democratic party opened the investigation not to gain any advantage in 2020, but instead to “uphold the laws of this nation, and investigate and punish wrongdoing when they occur.”“The House Democrats are fulfilling their duty to this country by holding the President accountable for his crimes,” Gregory said. Sophomore Brigid Harrington, vice president of College Democrats, said the issue of impeachment is of grave importance.“As such, any action must be taken with considerable caution,” Harrington said. ”At the same time, the American people deserve to know what transpired during President Trump’s phone call with the Ukrainian President, and if there was any potential wrongdoing. I believe that Speaker Pelosi has been effective in taking both of these important considerations into account.”Tags: College Democrats, College Republicans, President Donald Trump
Thomas also advises keeping them moist because they will dry out faster outside. After you put the plants into a bigger pot with fresh potting mix, fertilize them withone-quarter-strength fertilizer. Check for good drainage and water them thoroughly. “The whole process should take four to five days for vegetables and about two weeksfor ornamentals,” Thomas said. “Don’t put them in direct sunlight right away,” said Paul Thomas, a horticulturist withthe University of Georgia Extension Service. “It will burn leaves not used to highlight.” “They allow better air flow, better drainage and just look better,” he said. When you move plants outside, the leaves aren’t the only parts that need attention.Check the roots, too. “Shade, shade, shade is the key,” Thomas said. “Keep them shaded for a day or twountil turgid (filled out), then give them dappled light and slowly move them into longerand longer sunlight.” “Some plants will also need old leaves removed,” Thomas said. If you managed to save ferns through the winter, they may be thickly thatched withstraw. “You need to protect the plants from strong winds until new growth is established,” hesaid. “Most houseplants prefer dappled shade under trees.” When you first take outside the plants you stored indoors over the winter, or seedlingsyou’ve rooted inside, treat them like your own skin. Reintroduce them to the hotsummer sun slowly, or they too will get burned. If you started your seeds inside and are ready to plant them in your flower bed orvegetable garden, break them in gently. “Repot any root-bound plants when you move them outside,” Thomas said, “usually toa pot two inches larger all around the roots.” “Cut all the straw out, leaving any green leaves,” Thomas said. “New growth will flushafter a week or two under dappled shade if you add a quarter fertilizer and water.” Thomas always recommends repotting into clay pots. Remember to water seedlings more as you give them more light. When the bright summer sun peeks through and sunbathers take to the beaches, skingets burned. Plants are a bit like that, too.
Saint Michael’s College received a grant for $116,640 from the DavisEducational Foundation on May 5 for a program focused on helping integratenew faculty into teaching in a liberal arts college, President MarcvanderHeyden announced.The grant will support a New Instructors Program, which will include aseries of one-hour seminars addressing student learning styles, classroommanagement, effective pedagogy and understanding of the Saint Michael’sLiberal Studies requirement. It will also support a program linking afaculty-teaching mentor with each new faculty member to help him or herdevelop an effective teaching style.”What’s exciting is that this grant allows the college to work withincoming faculty members as they make the complicated transition fromgraduate programs at large universities to teaching at an undergraduateliberal arts college,” said Dr John Kenney, Saint Michael’s Dean of theCollege. “Above all it will help new faculty focus their efforts andtheir disciplinary learning on effective undergraduate instruction,” DeanKenney said.The grant will help new faculty “transition from the discipline-focusedscholarship of the typical Ph.D.-granting university to the moreinterconnected curriculum of the liberal arts college,” according to thegrant proposal.The project will extend over three years and will include some 32 newfaculty members, counting eight per year, and including those who began atSaint Michael’s during the 2002-2003 academic year.Located in Falmouth Maine, the Davis Educational Foundation, which awardedthe grant, was established by Stanton and Elisabeth Davis after hisretirement as chairman of Shaw’s Supermarkets, Inc.
Sign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York This 53-foot-long, 80-ton steel snow removal vehicle dubbed ‘Darth Vader’ is part of Long Island Rail Road’s winter weather arsenal. (Photo: MTA / LIRR)The weekend is coming early to the Long Island Rail Road after officials announced that train service will be limited to a typical Saturday-Sunday schedule on Friday because of a powerful winter storm barreling toward the Island.Reduced schedule also means the LIRR will not offer train service Friday on the West Hempstead branch or between Ronkonkoma and Greenport, officials said.The announcement was made by New York Gov. Andrew Cuomo, who just hours earlier said the Long Island Expressway will shut down at midnight until 5 a.m.“The safety of MTA riders and employees is the top priority of the MTA,” Cuomo said. “MTA employees have been out sanding and salting platforms and walkways, but conditions can become difficult quickly during a winter storm.”LIRR customers accustomed to departing from the railroad’s West Hempstead branch can instead catch a train from Hempstead, Lynbrook, Valley Stream or the Merillon Avenue station. The MTA will provide bus service to riders between Ronkonkoma and Greenport, officials said.The MTA said it has already taken precautions in the event that the impending blizzard lives up to predictions. Snow removal deployment has already been deployed to “key locations” and special anti-freeze trains are being utilized to coat the tracks in anticipation of icing. Extra LIRR personnel have also been called on to assist at critical locations.Despite the measures already being taken to battle the storm, the railroad warned that snow accumulation of 10-13 inches could force the LIRR to temporarily suspend service to make way for snow removal equipment to clear snow from tracks. The LIRR has at its disposal a large steel plow, dubbed “Darth Vader,” to help with snow removal.Forecasters are predicting between 8 to 10 inches of snow starting Thursday evening and freezing temperatures possibly dropping to 10 degrees below zero.