U.S. reports record 153,400 new Covid cases as Dr. Fauci urges Americans to be careful: ‘It is not futile’

first_imgWhile some, including President Donald Trump, have said increased testing is driving the rise in cases, the data doesn’t bear that out. The seven-day average of new tests on Thursday was over 1.4 million, up by about 8.3% compared with a week ago, according to a CNBC analysis of COVID Tracking Project data. The rise in cases far outpaces that with a week-over-week rise of more than 32%, on an average weekly basis.And the so-called positivity rate has been increasing, too. Epidemiologists say the percent of positive tests can be a helpful figure to determine whether an outbreak is expanding and whether an area is conducting enough testing. In the U.S., the seven-day average positivity rate rose to 9.1% from 7.2% a week ago, according to Hopkins data.The surge of the virus is beginning to overwhelm hospitals in some areas. Dr. Alan Kaplan, CEO of UW Health at the University of Wisconsin, said Thursday his system’s hospitals are overwhelmed in both rural and urban communities.“We are short of staff all times, either because they have Covid or they have some other illness and we need to rule out Covid before we bring them back to work,” he said on “Squawk on the Street.” “There is no surplus now.” Fauci added that “we need to pull more testing into the community” in order to identify people who don’t have symptoms but are infected and spreading the virus. Testing has increased substantially across the country, but as infection becomes more prevalent, as well, epidemiologists say even more testing is needed. – Advertisement – The United States reported another record one-day spike in Covid-19 cases on Thursday as the outbreak grows more severe and overwhelms some hospitals.The country reported more than 153,400 new cases on Thursday, according to data compiled by Johns Hopkins University. That’s the third-straight record one-day spike in cases in the U.S and has pushed the seven-day average of new cases over 131,400, up more than 32% compared with a week ago, according to a CNBC analysis of Hopkins data.It’s not just cases. There are currently more than 67,000 people hospitalized with Covid-19 across the country, more than at any other point during the pandemic, according to data from the COVID Tracking Project, which is run by journalists at The Atlantic. The number of people dying every day from the disease is ticking upward as well. – Advertisement –center_img Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said Friday that “a number of factors” are driving the outbreak, including people growing tired of following public health measures. He said that’s a particular issue as the country approaches Thanksgiving in about two weeks, when many Americans are expected to travel across the country to see family and friends, potentially bringing the virus with them.Fauci urged Americans to wear a mask, practice social distancing, wash hands frequently and to follow other public health measures.“If we do the things that are simple public health measures, that soaring will level and start to come down,” he said on CBS’ “This Morning.” “You add that to the help of a vaccine, we can turn this around. It is not futile.”- Advertisement – Spc. Demetrie Barnett of the Nevada National Guard administers a COVID-19 test during a preview of a free drive-thru COVID-19 testing site in the parking garage of the Texas Station Gambling Hall & Hotel on November 12, 2020 in North Las Vegas, Nevada.Ethan Miller | Getty Images – Advertisement –last_img read more

As Tensions Among Republicans Mount, Georgia’s Recount Proceeds Smoothly

first_imgThe secretary of state’s office declined Monday to release the results of the recounts from individual counties. But over the weekend Patrick Moore, a lawyer for the Biden campaign, said that Democrats had been keeping tabs on the county-by-county results and had found that while some discrepancies between the original counts and the recounts had emerged, they were minor and would not affect Mr. Biden’s front-runner status in the state.“As expected, the counties that have completed their audit thus far have shifted vote totals but almost imperceptibly, and thus far in favor of Joe Biden,” Mr. Moore said during a telephone news conference.With the newly discovered ballots in Floyd County, Mr. Biden’s lead will go from around 14,200 to around 13,300 votes, according to Mr. Sterling. The New York Times declared Mr. Biden the winner of Georgia’s 16 electoral votes on Friday, joining a number of major news organizations.- Advertisement – Mr. Sterling said that the Floyd County officials discovered the issue in the midst of doing the recount. Mr. Sterling called the error “gross incompetence” on the part of the Floyd County elections director, and said that Mr. Raffensperger had asked the director to step down.It was the Trump campaign that demanded a hand recount last week in a letter to Mr. Raffensperger. Shortly afterward, Mr. Raffensperger ordered the recount, which his office said is technically an audit. Mr. Raffensperger also hit back at Representative Doug Collins, who is overseeing Mr. Trump’s efforts in Georgia and who accused the secretary of state of caving in to pressure from Democrats. Mr. Raffensperger called Mr. Collins a “liar” and a “charlatan.”The extraordinary, labor-intensive effort to recount every vote in every one of Georgia’s 159 counties began Friday morning, and counties have until late Wednesday, just before midnight, to complete the work. As of Monday evening, 4.3 million ballots had been recounted, according to the secretary of state’s office, out of just under five million cast.- Advertisement –center_img – Advertisement –last_img read more

Firm gets funds for work on avian flu DNA vaccine

first_imgJun 7, 2006 (CIDRAP News) – Vical Inc., San Diego, announced today it would receive early access to $2.6 million in government funds to help it complete preclinical development of a DNA vaccine for avian influenza.Last September the National Institute of Allergy and Infectious Diseases (NIAID) awarded the company a $2.9 million challenge grant to develop the vaccine. In May the company reported the vaccine had protected mice and ferrets against a highly virulent strain of H5N1 avian flu virus and had protected mice against multiple human flu strains.On the basis of those results, the National Institutes of Health notified Vical that it had achieved the second milestone required under the challenge grant, the company said in a news release today.The new funds will be used to finish preclinical work on the vaccine and apply to the US Food and Drug Administration for permission to launch a phase 1 clinical trial, the company reported. The firm is seeking additional funds to support the phase 1 trial.DNA vaccines use small pieces of the target pathogen’s genetic material instead of a killed or weakened form of the whole pathogen. Vical says it makes DNA vaccines with simple bacterial fermentation methods that may allow rapid production of large amounts.David C. Klaslow, MD, Vical’s chief scientific officer, said the company’s DNA flu vaccines “have performed remarkably well in animal challenge studies, and this accelerated access to funding allows us to move forward ahead of our original schedule, which is quite important given the imminent threat posed by pandemic influenza.”The company has been collaborating with St. Jude Children’s Research Hospital in Memphis in the early development of the DNA flu vaccines. In reporting the results of animal experiments last month, the company said its three-component vaccine fully protected mice and ferrets against death and weight loss after exposure to an H5N1 virus, whereas animals that received a control vaccine all died. The three-component vaccine targeted one of the virus’s variable surface proteins and two conserved, or stable, core proteins, the company said.The company also said it tested DNA vaccines targeting only the two conserved viral proteins. In that study, 14 of 16 mice in each of two vaccine groups survived with moderate weight loss. “The study is the first to provide evidence that a vaccine targeting conserved influenza virus proteins without matched surface proteins can provide protection against such a highly virulent H5N1 flu strain,” the company said in a May 2 news release.In addition, the firm said the same vaccine formulation protected animals against two strains of human influenza in a previous study.”A vaccine that provides cross-protection against more than one strain of flu is important for addressing a pandemic flu threat because it is likely that the H5N1 virus could mutate before it becomes transmissible from human to human,” said Richard Webby, PhD, of St Jude Children’s Research Hospital, as quoted in a Vical release.When Vical first announced its NIAID grant last September, it said its goal was “to design a vaccine that could be developed and manufactured quickly and safely, without handling the infectious organism, and stockpiled longer than conventional vaccines.”See also:Jun 2 CIDRAP News story “Epidermal DNA flu vaccine shows promise in phase 1 trial”last_img read more

FDA warns Sanofi about problems at flu vaccine plant

first_imgJul 5, 2006 (CIDRAP News) – The Food and Drug Administration (FDA) on Jun 30 sent a warning letter to Sanofi Pasteur, Inc., about contamination in a component of Fluzone, the influenza vaccine the company is preparing for the 2006-07 season.Both the FDA and the company said they did not expect the problems to significantly limit production of the vaccine for this season. The company has said it plans to make about 50 million doses, which could be roughly half the US supply.The warning letter discusses contamination of one of the monovalent concentrates, a preparation of one of the three strains of killed flu virus used in the vaccine. The monovalent concentrates are mixed to make the trivalent vaccine, which protects against the three viral strains, the FDA said.According to the FDA, Sanofi Pasteur notified the FDA on Mar 31 about sterility failures in monovalent concentrates. The FDA inspected the company’s Swiftwater, Pa., facility from April 18 to 28 and issued a report to the company. After determining that the company’s response to the report was inadequate, the FDA issued the Jun 30 warning letter.The five-page letter describes a number of “significant deviations from current good manufacturing practices.” The letter says the company must take prompt corrective actions or risk facing enforcement steps, such as license suspension.According to a July 4 USA Today report, the FDA’s Karen Midthun said no more lots of monovalent vaccine have failed sterility testing, but “since we don’t know exactly what it was that caused the failure, we can’t know for sure if it has been corrected.” Midthun is deputy director of the FDA Center for Biologics Evaluation and Research.The failed lots of monovalent concentrate represented a small proportion of the total produced and were not used for further processing, said the FDA. The agency noted that influenza vaccine manufacturers generally produce monovalents of each strain throughout winter and spring and then assemble the final vaccine in early summer.David Johnson, director of scientific and medical affairs for Sanofi Pasteur, said the company believed that the contaminants came from organisms in the chicken eggs used to make the vaccine and that the company was quickly addressing the problem, according to USA Today.In February, Sanofi said it planned to produce about 50 million doses of Fluzone for US distribution, which would represent roughly half of the US flu vaccine supply. According to a Jul 3 Reuters report, the company said it was confident that it would supply 50 million doses in time for fall vaccinations.The Centers for Disease Control and Prevention said last week that vaccine manufacturers expect to make about 100 million doses of vaccine for US distribution in the upcoming fu season.After production problems with Chiron’s influenza vaccine in 2004, which led to serious vaccine shortages, the FDA instituted annual inspections of vaccine manufacturers in 2005. Following its inspection of the Sanofi Pasteur facility last year, the FDA recommended a list of corrective actions. During its recent inspection the FDA determined that some of the problems remained, along with additional concerns.last_img read more

Zadar and Madrid are connected by a regular line for the first time

first_imgFrom next season, Zadar and Madrid will be connected by a hard line for the first time.  By the way, Iberia Express is a low-cost subsidiary of the Spanish national airline Iberia, and tickets on the Zadar-Madrid route will be on sale as part of a code-share cooperation between the two companies. Iberia Express has announced a new route to Zadar in its summer flight schedule. The new line will be in operation from July 2 to August 31, 2019, on Tuesdays and Saturdays. center_img Photo: Iberia.comlast_img

Gastro Hvar is a new sales center for Mediterranean delicacies

first_imgSource / photo: Dalmatian portal; Facebook: Gastro Hvar The company “Gastro Hvar” specializes in food distribution in the HoReCa market segment, and its basic task is to distribute quality products in an adequate way, thanks to highly educated staff, who honed their knowledge and skills through decades of experience in all segments of food supply . The company’s mission is to enrich the offer of all professional cuisines on the island of Hvar, with high quality food and gastronomic delicacies. In order to show boaters the beauty of Mediterranean food and drinks, the newly opened center will also supply yachts. Brands such as Centaurus doo (Gastro Ribarnice Brač), Škokić doo (Mesnice Škokić), Fistonić doo (Fruits and vegetables), Purex doo (Croatian village products), Acrobat doo (Wine distribution), Nirs doo will be on sale. trade and distribution), Zigante Tartufi doo (Production, trade and distribution) which will enrich the entire offer of premium groceries on the island. The diverse range of products, from a diverse selection of fresh and frozen fish, meat, fruits and vegetables, includes a selection of world-famous cheeses, a rich delicacy program, the most prized alcoholic beverages, champagne, premium water, truffles and catering accessories. As an imperative in business, an individual approach is set for each customer, in order to meet their needs, then timely delivery and fulfillment of the requirements of valued customers, and the most important task is to provide excellent partner service to chefs, F&B managers and restaurant owners. In an effort to offer residents and tourists of the island of Hvar only the best gastronomic products, “Gastro Hvar” was opened, a retail and wholesale center, at the very entrance to the town of Hvar, reports the Dalmatian portal. The new shopping center will certainly improve the gastronomic offer of the island of Hvar, which is one of the most desirable destinations for island and nautical tourism.last_img read more

Andrea Pisac, author of the cookbook “Croatian Desserts”: Croatian gastronomic offer should focus more on traditional dishes

first_imgThe author of the book, doctor of anthropology, writer, travel blogger and winner of the City of Zagreb Award for Cultural Contribution, turned her inspiration into an interesting book, which is also the first cookbook of Croatian desserts written in English. Fifty recipes for traditional Croatian cakes from almost all parts of Croatia are immortalized in 515 attractive photos, which show the finished dessert, but also the preparation itself. It will be able to be used by enthusiasts without any experience in the kitchen, as well as those a little more skilled who want to improve their culinary skills. Numerous visitors of the Bulldog gastro pub showed how much desserts are a favorite and indispensable part of the Croatian gastronomic tradition, at the promotion of Croatian dessert chef “Croatian Desserts” Andrea Pisac. When asked how she came up with the idea to combine the recipes of autochthonous Croatian desserts into one cookbook, Andrea explained that the interest of the readers of her blog Croatia Honestly about traditional Croatian dishes was one of the main factors. “Through constant communication with them, I actually realized that people are very interested in getting to know Croatia through food, and especially through sweets. Since I am an anthropologist by profession, I am very interested in traditional food and a self-sustaining diet, so I set out to explore indigenous desserts and collect them in one cookbook.She said. The smell of the cake attracted both bloggers and journalists, a great food lover, Domagoj Jakopović Ribafish and Ashley Colburn, known for her great documentaries and great love for Croatia.  Although the cookbook is already available in bookstores and gift shops in Zagreb, Rijeka, Split and Zadar, as well as on the official website, Andrea has even bigger plans for its distribution and promotion. “The plans are to distribute the cookbook to all airports in Croatia, and we are in negotiations with many centers of the Croatian diaspora around the world, such as, for example, the presentation of the book on the east and west coasts of the United States. We are also in negotiations for direct distribution through Amazon”, She explained and added that”from the spring, the plan will direct the promotion to foreign tourists and will start expanding the distribution to even more gift shops, but also hotels.” “Gastronomy is definitely one of the key elements of the tourist offer”, Andrea thinks. “I think that currently this segment is best developed in Istria and Međimurje counties. Croatia should focus much more on traditional dishes and be proud of its simple dishes to which foreigners react the most. One of the fantastic examples of such dishes is soparnik, which is actually a very simple and poor dish, but there is no guest who is not delighted with it.”, She explained. Through stories that combine tradition with a vision of the future, Andrea has created a collection of Croatian culinary heritage. “Sweets are emotions, and emotions are the best way to connect what is separated, whether it is a bridge between the past, present and future, or it is different cultures that want to get to know each other. Therefore, this cookbook is an ideal gift and in fact another authentic Croatian souvenir, because it is known that one of the favorite ways to get to know a country and its culture is gastronomy.She said. The book “Croatian Desserts” is thematically divided into several chapters: Lazy Morning, Sunday Sweets, Special Occasions, Cakes, Christmas Sweets and Easter Sweets. Recipes are expressed in metric and imperial unit systems so they will be able to be followed by those who weigh the ingredients as well as those who measure them in cups and spoons. Each dessert has an introductory story – details about the origin of the dessert, the occasions in which it is eaten, the rituals and some perhaps already forgotten lines from the life of the cake. Another peculiarity of this book are the bilingual names with pronunciation.  Andrea places Croatian desserts in the context of European, world-famous dessert classics. She collected original recipes by word of mouth and field research, and their great value is authenticity. Various culinary and cultural stories about each of the selected cakes represent an ideal window into Croatian gastronomy, as well as into the Croatian way of life. The book presents desserts by which Croatia is already recognized abroad, such as walnut and poppy seeds, fritters, štruklji, paprenjaci, kremšnite, Međimurje gibanica, but also some forgotten recipes such as Kaiserschmarrn or water rolls. You can find the cookbook in selected bookstores and gift shops, as well as in the official one website.last_img read more